Hideki Wanibuchi Selected Research

Therapeutics

1/2023	Irradiation plus myeloid-derived suppressor cell-targeted therapy for overcoming treatment resistance in immunologically cold urothelial carcinoma.
1/2020	Myeloid-derived suppressor cells are essential partners for immune checkpoint inhibitors in the treatment of cisplatin-resistant bladder cancer.
4/2018	Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells.
12/2016	Anti-PD-L1 treatment enhances antitumor effect of everolimus in a mouse model of renal cell carcinoma.
1/2015	Percutaneous carbon dioxide treatment using a gas mist generator enhances the collateral blood flow in the ischemic hindlimb.
6/2014	SIRT2 knockdown increases basal autophagy and prevents postslippage death by abnormally prolonging the mitotic arrest that is induced by microtubule inhibitors.
3/2004	Lack of preventive efficacy of FK228, a histone deacetylase inhibitor, against N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in p53+/- and p53+/+ mice.

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Hideki Wanibuchi Research Topics

Disease

74	Neoplasms (Cancer) 08/2023 - 01/2002
62	Carcinogenesis 04/2024 - 01/2002
19	Urinary Bladder Neoplasms (Bladder Cancer) 12/2023 - 01/2000
18	Carcinoma (Carcinomatosis) 11/2023 - 01/2003
16	Body Weight (Weight, Body) 12/2018 - 05/2002
15	Hyperplasia 04/2023 - 01/2002
8	Adenocarcinoma 10/2017 - 01/2002
7	Hepatocellular Carcinoma (Hepatoma) 10/2020 - 04/2007
6	Fibrosis (Cirrhosis) 09/2023 - 01/2005
6	Adenoma (Adenomas) 07/2021 - 01/2002
6	Cystitis 11/2009 - 04/2003
5	Inflammation (Inflammations) 01/2022 - 11/2009
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2016 - 08/2008
5	Liver Cell Adenoma (Hepatocellular Adenoma) 01/2010 - 01/2006
4	Liver Neoplasms (Liver Cancer) 07/2021 - 07/2002
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 08/2003
4	Colonic Neoplasms (Colon Cancer) 03/2009 - 01/2002
4	Aberrant Crypt Foci 01/2005 - 09/2002
3	Non-alcoholic Fatty Liver Disease 09/2023 - 02/2017
3	Alcoholic Fatty Liver 09/2023 - 02/2017
3	Neoplasm Metastasis (Metastasis) 02/2017 - 03/2013
3	Papilloma (Papillomatosis) 12/2013 - 08/2002
3	Pancreatic Neoplasms (Pancreatic Cancer) 08/2013 - 03/2011
3	Diabetic Nephropathies (Diabetic Nephropathy) 05/2012 - 01/2011
2	Necrosis 01/2022 - 02/2010
2	Diabetes Mellitus 03/2021 - 01/2007
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2020 - 11/2018
2	Type 2 Diabetes Mellitus (MODY) 10/2020 - 03/2011
2	Starvation 10/2019 - 06/2014
2	Infections 01/2019 - 08/2008
2	Hypoxia (Hypoxemia) 04/2018 - 03/2014
2	Lung Neoplasms (Lung Cancer) 01/2017 - 08/2004

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 09/2023 - 08/2003
22	CarcinogensIBA 01/2017 - 01/2000
15	Biomarkers (Surrogate Marker)IBA 09/2023 - 03/2009
13	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 07/2021 - 01/2006
11	Drinking WaterIBA 08/2023 - 08/2004
10	Cacodylic Acid (Cacodylate)IBA 11/2023 - 01/2002
10	Glutathione Transferase (Glutathione S-Transferase)IBA 10/2018 - 08/2003
8	ArsenicIBA 11/2023 - 01/2002
8	Messenger RNA (mRNA)IBA 08/2023 - 08/2003
8	8-Hydroxy-2'-DeoxyguanosineIBA 10/2020 - 02/2002
7	ProteomeIBA 11/2018 - 07/2009
6	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 08/2004
6	1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)IBA 08/2017 - 12/2003
6	Ethanol (Ethyl Alcohol)IBA 03/2017 - 09/2002
5	ParaffinIBA 01/2024 - 04/2004
5	LipidsIBA 09/2023 - 03/2014
5	EnzymesIBA 10/2019 - 11/2005
5	Dimenhydrinate (DMH)FDA LinkGeneric 08/2017 - 12/2003
5	Phenobarbital (Luminal)FDA Link 01/2017 - 02/2002
5	ErbB Receptors (EGF Receptor)IBA 02/2016 - 08/2003
5	Proliferating Cell Nuclear Antigen (PCNA)IBA 04/2006 - 03/2002
4	Cadherins (E-Cadherin)IBA 01/2024 - 01/2006
4	AminesIBA 12/2023 - 06/2006
4	ButylhydroxybutylnitrosamineIBA 08/2022 - 12/2003
4	Cyclin D1IBA 07/2021 - 08/2002
4	NitrosaminesIBA 08/2017 - 03/2004
4	diphenylarsinic acidIBA 01/2017 - 11/2007
4	Thioacetamide (Thioacetamid)IBA 05/2008 - 01/2005
3	Formaldehyde (Formol)FDA Link 01/2024 - 05/2012
3	Glucose (Dextrose)FDA LinkGeneric 09/2023 - 12/2009
3	Arsenicals (Arsenic Compounds)IBA 08/2023 - 07/2002
3	Small Interfering RNA (siRNA)IBA 03/2021 - 03/2011
3	NF-kappa B (NF-kB)IBA 03/2017 - 04/2003
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 03/2017 - 01/2006
3	Propolis (Bee Bread)IBA 03/2017 - 09/2015
3	Indicators and Reagents (Reagents)IBA 05/2016 - 07/2009
3	CytokinesIBA 01/2016 - 05/2002
3	AzoxymethaneIBA 01/2007 - 07/2004
3	Transforming Growth Factor alpha (TGF-alpha)IBA 06/2006 - 01/2004
3	beta CateninIBA 01/2006 - 09/2005
3	4- (4- cyclohexyl- 2- methyloxazol- 5- yl)- 2- fluorobenzenesulfonamideIBA 01/2005 - 12/2003
3	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2005 - 12/2003
3	monomethylarsonic acid (MSMA)IBA 08/2004 - 07/2002
2	VimentinIBA 01/2024 - 12/2018
2	RNA (Ribonucleic Acid)IBA 01/2024 - 08/2023
2	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 01/2020
2	CateninsIBA 08/2022 - 02/2017
2	Immune Checkpoint InhibitorsIBA 06/2022 - 01/2020
2	SeptinsIBA 07/2021 - 04/2010
2	Polysaccharides (Glycans)IBA 10/2020 - 01/2016
2	AntibodiesIBA 01/2020 - 03/2011
2	Histones (Histone)IBA 01/2020 - 07/2009
2	diisopropanolnitrosamineIBA 08/2017 - 01/2002
2	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 08/2017 - 01/2017
2	Dextrans (Dextran)FDA Link 03/2017 - 01/2016
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 03/2017 - 01/2016
2	Estrogens (Estrogen)FDA Link 11/2016 - 05/2005
2	ENNGIBA 11/2016 - 03/2012
2	N-nitroso-tris-chloroethylureaIBA 02/2016 - 12/2013
2	AntioxidantsIBA 01/2016 - 06/2010
2	propylene dichlorideIBA 05/2015 - 01/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2015 - 01/2007
2	AntigensIBA 01/2015 - 03/2011

Therapy/Procedure

7	Therapeutics 01/2023 - 03/2004
4	Lasers (Laser) 01/2015 - 07/2009
4	Chemoprevention 01/2007 - 01/2000
3	Oral Administration 01/2016 - 01/2002
2	Immunotherapy 06/2022 - 12/2016